Biotechnologist Cover Letter Examples & Writing Guide

Dear Genentech Team, I am writing to express my strong interest in the Research Scientist position in Protein Engineering at Genentech. With my PhD in Biotechnology and 4 years of post-doctoral experience, I am excited to contribute to the development of innovative biotherapeutics. At Amgen, I have conducted protein engineering research: • Designed and engineered 20+ therapeutic antibody variants with improved pharmacokinetic properties • Utilized directed evolution and rational design approaches to optimize protein stability and function • Expressed and purified recombinant proteins using mammalian cell culture systems • Characterized protein variants using biochemical and biophysical techniques including SPR and DSC • Collaborated with process development teams to ensure manufacturability of engineered proteins • Published 8 peer-reviewed articles on antibody engineering in high-impact journals • Presented research findings at international biotechnology conferences Genentech's leadership in biologics development and commitment to scientific excellence inspire me. Your innovative pipeline and groundbreaking research represent the forefront of biotechnology. I would welcome the opportunity to discuss how my protein engineering expertise can contribute to Genentech's mission. Sincerely, Dr. Sarah Chen, PhD

Dear Moderna Team, I am excited to apply for the Senior Scientist position in mRNA Technology at Moderna. With expertise in nucleic acid chemistry and RNA biology, I am passionate about advancing mRNA therapeutics and vaccines. At CureVac, I have developed mRNA technologies: • Designed and optimized mRNA constructs for improved translation efficiency and reduced immunogenicity • Developed lipid nanoparticle formulations for enhanced mRNA delivery • Conducted in vitro and in vivo studies evaluating mRNA expression and efficacy • Optimized manufacturing processes for mRNA production and purification • Collaborated with immunology teams on vaccine candidate development • Contributed to 3 IND applications for mRNA therapeutic programs • Published research on mRNA vaccine platforms in Nature Biotechnology Moderna's revolutionary mRNA platform and rapid vaccine development inspire me. Your technology has transformed medicine and represents the future of therapeutics. I look forward to discussing how my mRNA expertise can contribute to Moderna's pipeline. Best regards, Dr. Michael Rodriguez, PhD

Dear Illumina Team, I am writing to apply for the Applications Scientist position in Genomics at Illumina. With next-generation sequencing expertise and strong customer-facing skills, I am excited to support researchers utilizing Illumina technologies. At Thermo Fisher Scientific, I have provided genomics applications support: • Provided technical support to 100+ customers on NGS workflows and data analysis • Conducted on-site training at customer laboratories teaching best practices for library preparation and sequencing • Troubleshot experimental issues resolving technical problems and optimizing protocols • Developed application notes and technical bulletins documenting sequencing workflows • Presented webinars and workshops educating researchers on genomics technologies • Collaborated with product development teams providing customer feedback for product improvements • Achieved 95% customer satisfaction scores through excellent technical support Illumina's leadership in genomics and commitment to advancing precision medicine inspire me. Your sequencing platforms enable groundbreaking discoveries worldwide. I would be honored to discuss how my genomics expertise can support Illumina's customers. Sincerely, Dr. Emily Park, PhD

Dear Regeneron Team, I am excited to apply for the Research Associate position in Cell Biology at Regeneron. With my Master's degree in Cell Biology and 2 years of industry experience, I am passionate about contributing to drug discovery research. At Bristol Myers Squibb, I have conducted cell biology research: • Performed cell-based assays evaluating drug candidate activity including proliferation, apoptosis, and signaling pathway activation • Maintained mammalian cell lines ensuring optimal culture conditions and cell health • Conducted immunofluorescence microscopy imaging cellular structures and protein localization • Performed Western blotting and ELISA assays quantifying protein expression and modifications • Analyzed flow cytometry data characterizing cell populations and marker expression • Maintained detailed electronic notebooks documenting experimental procedures and results • Collaborated with medicinal chemistry teams on structure-activity relationship studies Regeneron's innovative approach to biologics discovery and commitment to scientific rigor inspire me. Your VelociSuite technologies represent cutting-edge drug development. I look forward to discussing how my cell biology skills can contribute to Regeneron's research. Best regards, Jennifer Lee, MS

Dear Novartis Team, I am writing to express my interest in the Bioprocess Engineer position in Biomanufacturing at Novartis. With bioprocess engineering expertise and manufacturing experience, I am excited to optimize production of life-saving biologics. At Lonza, I have worked in biomanufacturing: • Developed and optimized CHO cell culture processes for monoclonal antibody production • Scaled up processes from bench-scale to 2000L bioreactors ensuring consistent product quality • Performed process characterization studies defining critical process parameters • Troubleshot manufacturing deviations identifying root causes and implementing corrective actions • Collaborated with analytical teams on product quality assessment and release testing • Authored technical reports and regulatory documents supporting IND and BLA submissions • Implemented continuous improvement initiatives increasing productivity by 20% Novartis' commitment to manufacturing excellence and patient access inspires me. Your global manufacturing network ensures life-saving medicines reach patients worldwide. I would welcome the opportunity to discuss how my bioprocess expertise can contribute to Novartis. Sincerely, David Anderson, PhD

Dear CRISPR Therapeutics Team, I am excited to apply for the Scientist position in Gene Editing at CRISPR Therapeutics. With CRISPR-Cas9 expertise and passion for genome engineering, I am committed to developing transformative genetic medicines. At Editas Medicine, I have worked on gene editing: • Designed and validated guide RNAs for efficient and specific CRISPR-mediated gene editing • Optimized electroporation conditions for CRISPR delivery to primary human cells • Performed genome editing in T cells and hematopoietic stem cells for therapeutic applications • Characterized edited cell populations using flow cytometry and genomic sequencing • Assessed off-target editing using whole-genome sequencing and bioinformatics analysis • Contributed to preclinical development of ex vivo gene editing therapies • Presented research on CRISPR gene editing at ASGCT annual meeting CRISPR Therapeutics' pioneering work in gene editing therapies inspires me. Your clinical programs demonstrate the transformative potential of genome engineering. I look forward to discussing how my gene editing expertise can contribute to CRISPR Therapeutics. Best regards, Dr. Amanda Foster, PhD

Dear 10x Genomics Team, I am writing to apply for the Field Application Scientist position at 10x Genomics. With single-cell genomics expertise and enthusiasm for customer engagement, I am excited to support researchers utilizing 10x platforms. At BD Biosciences, I have provided field applications support: • Supported 50+ customers in academic and biotech institutions on single-cell analysis workflows • Conducted product demonstrations showcasing capabilities of single-cell platforms • Provided pre-sales technical consultation helping customers design experiments • Troubleshot technical issues ensuring successful experiment outcomes • Developed custom analysis pipelines for customer-specific applications • Presented scientific talks at conferences and symposia promoting platform adoption • Achieved sales targets through excellent technical support driving customer satisfaction 10x Genomics' revolutionary single-cell technologies inspire me. Your platforms enable unprecedented resolution in biological research. I would be honored to discuss how my single-cell expertise can support 10x customers. Sincerely, Carlos Martinez, PhD