Physician Assistant Cover Letter Examples & Writing Guide

Written ByBen Broch

August 7, 2025

We analyzed 1,000+ physician assistant cover letter examples cover letters and job listings to reveal what employers really want. Use these insights to craft a compelling letter and resume that align with today's trends.

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Physician Assistant Cover Letter Template

FIRST AND LAST NAME Email: your.email@email.com Phone: (123) 456-7891 LinkedIn: linkedin.com/in/yourprofile [Today's Date] [Hiring Manager's Name] [Company Name] [Company Address] Dear [Hiring Manager's Name], I am writing to express my strong interest in the Physician Assistant position at [Company Name]. With [X years] of experience in [relevant field], I am confident that my skills and passion make me an ideal candidate for this role. In my current position as [Current Role] at [Current Company], I have: • [Achievement 1 - Quantify with numbers when possible] • [Achievement 2 - Focus on relevant skills] • [Achievement 3 - Highlight impact] I am particularly drawn to [Company Name] because [specific reason related to company mission/values/projects]. I believe my experience in [relevant skill area] would contribute significantly to your team's continued success. Thank you for considering my application. I look forward to discussing how my background and enthusiasm can contribute to [Company Name]'s goals. Sincerely, [Your Name]

Customize this template with your specific details and achievements

Real Physician Assistant Cover Letter Examples

Physician Assistant - Primary Care

Mayo Clinic

Example #1

Dear Hiring Manager, I am writing to express my strong interest in the Primary Care Physician Assistant position at Mayo Clinic. With 5 years of experience as a PA-C in primary care and commitment to patient-centered medicine, I am excited to contribute to Mayo Clinic's tradition of excellence. In my current role at a busy primary care practice, I have: • Managed a diverse patient panel with acute, chronic, and preventive care needs • Achieved top-decile quality metrics for chronic disease management • Performed office procedures including skin biopsies, joint injections, and suturing • Collaborated with supervising physicians on complex medical decision-making • Participated in quality improvement initiatives improving patient outcomes Mayo Clinic's team-based approach and commitment to the best interest of the patient aligns with my professional values. I would welcome the opportunity to discuss how my experience can contribute to Mayo Clinic's primary care team. Sincerely, Michael Thompson, PA-C

Physician Assistant - Cardiovascular Surgery

Cleveland Clinic

Example #2

Dear Hiring Manager, I am excited to apply for the Cardiovascular Surgery Physician Assistant position at Cleveland Clinic. With specialized experience as first assist in cardiac surgery, I am eager to join your world-renowned cardiac surgery program. My cardiovascular surgery PA experience includes: • First assisted on 200+ cardiac cases including CABG, valve, and aortic surgery • Performed saphenous vein and radial artery harvesting • Managed pre-operative evaluation and post-operative care in CVICU • Experience with temporary pacemakers, chest tubes, and hemodynamic monitoring • Collaborated with cardiac surgeons on complex patient management Cleveland Clinic's leadership in cardiovascular surgery inspires me. I am excited about the opportunity to contribute to your surgical excellence. I would love to discuss how my cardiac surgery experience can support your team. Best regards, Sarah Chen, PA-C

Physician Assistant - Neurosurgery

Johns Hopkins Hospital

Example #3

Dear Hiring Manager, I am writing to apply for the Neurosurgery Physician Assistant position at Johns Hopkins Hospital. With specialized experience in neurosurgical care and passion for advancing neurological medicine, I am excited to contribute to Hopkins' renowned neurosurgery department. My neurosurgery PA experience includes: • First assisted on craniotomies, spine surgeries, and neurointerventional procedures • Managed neurosurgery ICU patients including ICP monitoring and EVD management • Performed lumbar punctures, wound care, and post-operative evaluations • Collaborated with neurosurgeons on complex surgical planning • Participated in resident education and tumor board conferences Johns Hopkins' leadership in neurosurgery and commitment to innovation aligns with my career goals. I would welcome the opportunity to discuss my qualifications for this position. Sincerely, David Park, PA-C

Physician Assistant - Emergency Medicine

Stanford Health Care

Example #4

Dear Hiring Manager, I am thrilled to apply for the Emergency Medicine Physician Assistant position at Stanford Health Care. With experience in high-volume emergency departments and passion for acute care, I am excited to contribute to Stanford's emergency medicine program. In my current emergency medicine role, I have: • Evaluated and treated 25+ patients per shift across all acuity levels • Managed chest pain, abdominal emergencies, and trauma independently • Performed procedures including intubation, chest tubes, and central lines • Collaborated with emergency physicians on critical resuscitations • Maintained efficiency while ensuring thorough evaluation Emergency medicine requires clinical acuity and ability to thrive under pressure. I am committed to excellent patient care in high-stakes situations. I would love to discuss how my EM experience can contribute to Stanford. Best regards, Jennifer Williams, PA-C, EMT-P

Physician Assistant - Orthopedic Surgery

Orthopedic Associates

Example #5

Dear Hiring Manager, I am writing to express my interest in the Orthopedic Surgery Physician Assistant position. With specialized experience in orthopedics and passion for sports medicine, I am excited to contribute to your surgical practice. My orthopedic PA experience includes: • First assisted on 300+ orthopedic procedures including arthroplasty and arthroscopy • Managed fracture care, casting, and post-operative rehabilitation • Performed joint injections, aspiration, and casting/splinting • Evaluated patients in clinic and determined surgical candidacy • Collaborated with orthopedic surgeons across subspecialties Orthopedics combines surgical skill with functional restoration. I am committed to helping patients return to active lives. I would welcome the opportunity to discuss how I can contribute to your practice. Sincerely, Kevin Martinez, PA-C

Physician Assistant - Hospitalist

University Hospital

Example #6

Dear Hiring Manager, I am excited to apply for the Hospitalist Physician Assistant position at University Hospital. With experience managing complex inpatients and passion for internal medicine, I am eager to join your hospitalist team. My hospital medicine experience includes: • Managed 15-20 inpatients daily with diverse medical conditions • Coordinated care with specialists, case management, and discharge planning • Performed bedside procedures including paracentesis, thoracentesis, and lumbar puncture • Led family meetings and goals of care discussions • Collaborated with teaching physicians in academic medical center Hospital medicine requires excellent clinical reasoning and communication. I am committed to patient safety and care coordination. I would love to discuss how my hospitalist experience can contribute to your team. Best regards, Amanda Torres, PA-C

Physician Assistant - Dermatology

Dermatology Specialists

Example #7

Dear Hiring Manager, I am writing to apply for the Dermatology Physician Assistant position. With specialized training in dermatology and passion for skin health, I am excited to provide comprehensive dermatologic care. My dermatology PA experience includes: • Diagnosed and treated medical, surgical, and cosmetic dermatologic conditions • Performed skin biopsies, excisions, and Mohs surgery wound closures • Managed acne, psoriasis, eczema, and skin cancer surveillance • Performed cosmetic procedures including Botox and dermal fillers • Strong dermoscopy skills and commitment to skin cancer detection Dermatology combines visual diagnosis with procedural skill. I am committed to improving patients' skin health and confidence. I would welcome the opportunity to discuss how I can contribute to your practice. Sincerely, Emily Chen, PA-C

Physician Assistant - Rural Medicine

Rural Health Clinic

Example #8

Dear Hiring Manager, I am excited to apply for the Physician Assistant position at your rural health clinic. With broad clinical training and commitment to underserved communities, I am passionate about bringing healthcare to rural areas. My relevant experience includes: • Rotations in rural and underserved settings during PA training • Experience with broad scope including primary care, urgent care, and procedures • Ability to practice independently with physician collaboration • Cultural competency and commitment to community health • Willingness to provide on-call coverage and adapt to community needs Rural medicine requires versatility and dedication. I am committed to serving patients who face barriers to care. I would love to discuss how my skills can contribute to your rural health mission. Best regards, Robert Johnson, PA-C

New Grad Physician Assistant Cover Letter

Starting your career? Focus on your education, clinical rotations, internships, and relevant coursework. Emphasize your enthusiasm and willingness to learn.

Pro tip: Highlight any volunteer work, part-time positions, or academic projects that demonstrate relevant skills for the role.

Experienced Physician Assistant Cover Letter

With years of experience, focus on your achievements, leadership roles, and measurable impact. Use specific examples and metrics to demonstrate your value.

Key focus areas: Leadership experience, process improvements, mentoring, specialized certifications, and quantifiable achievements.

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